Good news: a billionaire is funding research on diet, trying to correct the mostly astonishingly unsound research that has been done so far.
Bad news: some--most?--of the new research, while better, will still be grossly irrelevant.
Rudolph Leibel, one of the researchers working on the consortium study at Columbia, also has similar doubts—not least because his own research fully supports the calories-in/calories-out model, which holds that all calories have equal impact on our weight. When Leibel had participants in one study drink formulas with the same number of calories but hugely different proportions of fat and carbohydrates, he saw no difference in the amount of energy they burned.
This is great if you're eating predetermined foods under controlled conditions. But I'm not. And most people aren't. The types of foods you eat and the times you eat can, it seems to me, affect your desire to eat. And that's at least three-quarters of the battle.